| Peer-Reviewed

Research Progress of Unexplained Headache and Potential Oral and Maxillofacial Diseases

Received: 13 September 2022     Accepted: 29 September 2022     Published: 11 October 2022
Views:       Downloads:
Abstract

Headache is a common nervous system symptom with complex causes, including neurogenic, odontogenic, vascular, infectious and so on. Headache is generally manifested as pain in the region above the skull, orbit and occipital bone. But sometimes it also involves pain in the oral and maxillofacial region, because the craniofacial region is closely adjacent to the oral anatomy. Some oral diseases, such as pulpitis, temporomandibular joint disorder syndrome, and oral mucosal disease, can not only cause pain at the primary site, but also show head and face pain. Therefore, headache is easily confused with some oral diseases in clinical diagnosis. A large number of clinical reports at home and abroad have analyzed the correlation between neurologic diseases and oral diseases. This paper attempts to analyze the internal relationship between the two from clinical manifestations, pathogenesis and other aspects, focusing on the discussion of headache caused by oral diseases, which is meaningful for stomatologists and neurologists, and is conducive to expanding the thinking of oral disease research and diagnosis and treatment.

Published in American Journal of Internal Medicine (Volume 10, Issue 5)
DOI 10.11648/j.ajim.20221005.11
Page(s) 92-95
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Headache, Pulpitis, Temporomandibular Disorders, Oral Mucosal Disease

References
[1] Arora S, Cooper PR, Friedlander LT, et al. Potential application of immunotherapy for modulation of pulp inflammation: opportunities for vital pulp treatment. Int Endod J. 2021; 54 (8): 1263-1274.
[2] Schwager S, Detmar M. Inflammation and Lymphatic Function. Front Immunol. 2019; 10: 308. Published 2019 Feb 26.
[3] Li ZY, Zhang YP, Zhang J, et al. The possible involvement of JNK activation in the spinal dorsal horn in bortezomib-induced allodynia: the role of TNF-α and IL-1β. J Anesth. 2016; 30 (1): 55-63.
[4] Ding HH, Zhang SB, Lv YY, et al. TNF-α/STAT3 pathway epigenetically upregulates Nav1.6 expression in DRG and contributes to neuropathic pain induced by L5-VRT. J Neuroinflammation. 2019; 16 (1): 29.
[5] Yarushkina NI, Filaretova LP. The peripheral corticotropin-releasing factor (CRF)-induced analgesic effect on somatic pain sensitivity in conscious rats: involving CRF, opioid and glucocorticoid receptors. Inflammopharmacology. 2018; 26 (2): 305-318.
[6] Munasinghe MA, Weerasinghe V, Samarakoon MA. "Pointing forehead": a new physical sign in migraine. Springerplus. 2016; 5 (1): 194.
[7] Milcent CPF, da Silva TG, Baika LM, et al. Morphologic, Structural, and Chemical Properties of Pulp Stones in Extracted Human Teeth. J Endod. 2019; 45 (12): 1504-1512.
[8] Guarda-Nardini L, Trojan D, Paolin A, Manfredini D. Management of temporomandibular joint degenerative disorders with human amniotic membrane: hypothesis of action. Med Hypotheses 2017; 104: 68–71.
[9] Renton T. Tooth-Related Pain or Not?. Headache. 2020; 60 (1): 235-246.
[10] Piekartz HV, Rösner C, Batz A, Hall T, Ballenberger N. Bruxism, temporomandibular dysfunction and cervical impairments in females - Results from an observational study. Musculoskelet Sci Pract. 2020; 45: 102073.
[11] Edmeads J. Cervicogenic headache. Pain Physician, 2016; 1: 119-122.
[12] Greenbaum T, Dvir Z, Emodi-Perlman A, Reiter S, Rubin P, Winocur E. The association between specific temporomandibular disorders and cervicogenic headache. Musculoskelet Sci Pract. 2021; 52: 102321.
[13] Takran U, Unka M. A deep learning based decision support system for diagnosis of Temporomandibular joint disorder. Applied Acoustics. 182.
[14] Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018; 38 (1): 1-211.
[15] Rnold M Headache classification committee of international headache society (IHS) the international classification of headache disorders, 3rd edition [J]. Cephalalgia, 2018, 38.
[16] Ziegeler C. May A. Facial presentations of migraine, TACs, and other paroxysmal facial pain syndromes. Neurology, 2019, 93 (12): e1138-e1147.
[17] Iyengar S, Johnson KW, Ossipov MH, Aurora SK. CGRP and the Trigeminal System in Migraine. Headache. 2019; 59 (5): 659-681.
[18] Kuzawińska O, Lis K, Cessak G, Mirowska-Guzel D, Bałkowiec-Iskra E. Targeting of calcitonin gene-related peptide action as a new strategy for migraine treatment. Neurol Neurochir Pol. 2016; 50 (6): 463-467.
[19] Hc A, Jlb C, Kb A, et al. A case of Melkersson-Rosenthal syndrome from sub-Saharan Africa. Neuroimmunology Reports, 2021; 1.
[20] Miest R, Bruce A, Rogers RS 3rd. Orofacial granulomatosis. Clin Dermatol. 2016; 34 (4): 505-513.
[21] Rozen TD. Melkersson-Rosenthal syndrome presenting as a new daily persistent headache: relief with dapsone. Cephalalgia. 2001; 21 (9): 924-925.
[22] Kosovali BD, Yavuz A, Yesiler FI, Bayar MK. Melkersson-Rosenthal Syndrome: A Rare Cause of Recurrent Facial Nerve Palsy and Acute Respiratory Distress Syndrome. Case Rep Neurol Med. 2018; 2018: 1373581.
Cite This Article
  • APA Style

    Di Chen, Si Yu Tao, Tian Le Chen, Ying Yu Luo, Zhu Ling Guo. (2022). Research Progress of Unexplained Headache and Potential Oral and Maxillofacial Diseases. American Journal of Internal Medicine, 10(5), 92-95. https://doi.org/10.11648/j.ajim.20221005.11

    Copy | Download

    ACS Style

    Di Chen; Si Yu Tao; Tian Le Chen; Ying Yu Luo; Zhu Ling Guo. Research Progress of Unexplained Headache and Potential Oral and Maxillofacial Diseases. Am. J. Intern. Med. 2022, 10(5), 92-95. doi: 10.11648/j.ajim.20221005.11

    Copy | Download

    AMA Style

    Di Chen, Si Yu Tao, Tian Le Chen, Ying Yu Luo, Zhu Ling Guo. Research Progress of Unexplained Headache and Potential Oral and Maxillofacial Diseases. Am J Intern Med. 2022;10(5):92-95. doi: 10.11648/j.ajim.20221005.11

    Copy | Download

  • @article{10.11648/j.ajim.20221005.11,
      author = {Di Chen and Si Yu Tao and Tian Le Chen and Ying Yu Luo and Zhu Ling Guo},
      title = {Research Progress of Unexplained Headache and Potential Oral and Maxillofacial Diseases},
      journal = {American Journal of Internal Medicine},
      volume = {10},
      number = {5},
      pages = {92-95},
      doi = {10.11648/j.ajim.20221005.11},
      url = {https://doi.org/10.11648/j.ajim.20221005.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20221005.11},
      abstract = {Headache is a common nervous system symptom with complex causes, including neurogenic, odontogenic, vascular, infectious and so on. Headache is generally manifested as pain in the region above the skull, orbit and occipital bone. But sometimes it also involves pain in the oral and maxillofacial region, because the craniofacial region is closely adjacent to the oral anatomy. Some oral diseases, such as pulpitis, temporomandibular joint disorder syndrome, and oral mucosal disease, can not only cause pain at the primary site, but also show head and face pain. Therefore, headache is easily confused with some oral diseases in clinical diagnosis. A large number of clinical reports at home and abroad have analyzed the correlation between neurologic diseases and oral diseases. This paper attempts to analyze the internal relationship between the two from clinical manifestations, pathogenesis and other aspects, focusing on the discussion of headache caused by oral diseases, which is meaningful for stomatologists and neurologists, and is conducive to expanding the thinking of oral disease research and diagnosis and treatment.},
     year = {2022}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Research Progress of Unexplained Headache and Potential Oral and Maxillofacial Diseases
    AU  - Di Chen
    AU  - Si Yu Tao
    AU  - Tian Le Chen
    AU  - Ying Yu Luo
    AU  - Zhu Ling Guo
    Y1  - 2022/10/11
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ajim.20221005.11
    DO  - 10.11648/j.ajim.20221005.11
    T2  - American Journal of Internal Medicine
    JF  - American Journal of Internal Medicine
    JO  - American Journal of Internal Medicine
    SP  - 92
    EP  - 95
    PB  - Science Publishing Group
    SN  - 2330-4324
    UR  - https://doi.org/10.11648/j.ajim.20221005.11
    AB  - Headache is a common nervous system symptom with complex causes, including neurogenic, odontogenic, vascular, infectious and so on. Headache is generally manifested as pain in the region above the skull, orbit and occipital bone. But sometimes it also involves pain in the oral and maxillofacial region, because the craniofacial region is closely adjacent to the oral anatomy. Some oral diseases, such as pulpitis, temporomandibular joint disorder syndrome, and oral mucosal disease, can not only cause pain at the primary site, but also show head and face pain. Therefore, headache is easily confused with some oral diseases in clinical diagnosis. A large number of clinical reports at home and abroad have analyzed the correlation between neurologic diseases and oral diseases. This paper attempts to analyze the internal relationship between the two from clinical manifestations, pathogenesis and other aspects, focusing on the discussion of headache caused by oral diseases, which is meaningful for stomatologists and neurologists, and is conducive to expanding the thinking of oral disease research and diagnosis and treatment.
    VL  - 10
    IS  - 5
    ER  - 

    Copy | Download

Author Information
  • School of Dentistry, Hainan Medical University, Haikou, PR China

  • School of Dentistry, Hainan Medical University, Haikou, PR China

  • School of Dentistry, Hainan Medical University, Haikou, PR China

  • School of Dentistry, Hainan Medical University, Haikou, PR China

  • School of Dentistry, Hainan Medical University, Haikou, PR China

  • Sections