Researched the effect of chronic toxic maternal hepatitis on the cytometric features of immunocompetent cells (ICCls) of mammary gland tissues of the female and the jejunum of the offspring during breastfeeding. For morphological researches, pieces of the right inguinal mammary gland of female outbred rats with heliotrine hepatitis and the jejunum of the lean intestine of the offspring on days 1, 3, 7, 15 and 21 of lactation were used. Cytometric researches were carried out on semi-thin sections stained with methylene blue and pyronin G. It was established that in the last stages of pregnancy and in the first week after the onset of lactation, there is an increase in migration to the terminal secretory sections of the mammary gland of the ICCls, which indicates the participation of the mammary glands in the transfer of adoptive immunity to offspring and in maintaining the immune homeostasis of the small intestine, which decreases as the immune apparatus of the small intestine develops. A decrease in the number of ICCls migrating to the lactating mammary gland in case of mother's CTH negatively affects both immune adaptation and the structural and functional development and maturation of the immune apparatus of the jejunum of the offspring during breastfeeding.
Published in | American Journal of Internal Medicine (Volume 10, Issue 2) |
DOI | 10.11648/j.ajim.20221002.12 |
Page(s) | 28-33 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2022. Published by Science Publishing Group |
Hepatitis, Mammary Gland, Lactation, Small Intestine, Offspring, Immunocompetent Cells
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APA Style
Khasanov Bakhtiyor Burtkhanovich. (2022). Extragenital Pathology and Immunocompetent Cells Relations of Lactating Breast Gland and Offspring Jejunum. American Journal of Internal Medicine, 10(2), 28-33. https://doi.org/10.11648/j.ajim.20221002.12
ACS Style
Khasanov Bakhtiyor Burtkhanovich. Extragenital Pathology and Immunocompetent Cells Relations of Lactating Breast Gland and Offspring Jejunum. Am. J. Intern. Med. 2022, 10(2), 28-33. doi: 10.11648/j.ajim.20221002.12
AMA Style
Khasanov Bakhtiyor Burtkhanovich. Extragenital Pathology and Immunocompetent Cells Relations of Lactating Breast Gland and Offspring Jejunum. Am J Intern Med. 2022;10(2):28-33. doi: 10.11648/j.ajim.20221002.12
@article{10.11648/j.ajim.20221002.12, author = {Khasanov Bakhtiyor Burtkhanovich}, title = {Extragenital Pathology and Immunocompetent Cells Relations of Lactating Breast Gland and Offspring Jejunum}, journal = {American Journal of Internal Medicine}, volume = {10}, number = {2}, pages = {28-33}, doi = {10.11648/j.ajim.20221002.12}, url = {https://doi.org/10.11648/j.ajim.20221002.12}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20221002.12}, abstract = {Researched the effect of chronic toxic maternal hepatitis on the cytometric features of immunocompetent cells (ICCls) of mammary gland tissues of the female and the jejunum of the offspring during breastfeeding. For morphological researches, pieces of the right inguinal mammary gland of female outbred rats with heliotrine hepatitis and the jejunum of the lean intestine of the offspring on days 1, 3, 7, 15 and 21 of lactation were used. Cytometric researches were carried out on semi-thin sections stained with methylene blue and pyronin G. It was established that in the last stages of pregnancy and in the first week after the onset of lactation, there is an increase in migration to the terminal secretory sections of the mammary gland of the ICCls, which indicates the participation of the mammary glands in the transfer of adoptive immunity to offspring and in maintaining the immune homeostasis of the small intestine, which decreases as the immune apparatus of the small intestine develops. A decrease in the number of ICCls migrating to the lactating mammary gland in case of mother's CTH negatively affects both immune adaptation and the structural and functional development and maturation of the immune apparatus of the jejunum of the offspring during breastfeeding.}, year = {2022} }
TY - JOUR T1 - Extragenital Pathology and Immunocompetent Cells Relations of Lactating Breast Gland and Offspring Jejunum AU - Khasanov Bakhtiyor Burtkhanovich Y1 - 2022/04/26 PY - 2022 N1 - https://doi.org/10.11648/j.ajim.20221002.12 DO - 10.11648/j.ajim.20221002.12 T2 - American Journal of Internal Medicine JF - American Journal of Internal Medicine JO - American Journal of Internal Medicine SP - 28 EP - 33 PB - Science Publishing Group SN - 2330-4324 UR - https://doi.org/10.11648/j.ajim.20221002.12 AB - Researched the effect of chronic toxic maternal hepatitis on the cytometric features of immunocompetent cells (ICCls) of mammary gland tissues of the female and the jejunum of the offspring during breastfeeding. For morphological researches, pieces of the right inguinal mammary gland of female outbred rats with heliotrine hepatitis and the jejunum of the lean intestine of the offspring on days 1, 3, 7, 15 and 21 of lactation were used. Cytometric researches were carried out on semi-thin sections stained with methylene blue and pyronin G. It was established that in the last stages of pregnancy and in the first week after the onset of lactation, there is an increase in migration to the terminal secretory sections of the mammary gland of the ICCls, which indicates the participation of the mammary glands in the transfer of adoptive immunity to offspring and in maintaining the immune homeostasis of the small intestine, which decreases as the immune apparatus of the small intestine develops. A decrease in the number of ICCls migrating to the lactating mammary gland in case of mother's CTH negatively affects both immune adaptation and the structural and functional development and maturation of the immune apparatus of the jejunum of the offspring during breastfeeding. VL - 10 IS - 2 ER -